Uridine triphosphate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

三磷酸尿苷通过激活 P2Y2 受体来增加人癌性胰管上皮细胞的增殖。

Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.

Western Blot Analysis Cell Line:RT4-D6P2T cells Concentration:250 μM Incubation Time:5 min, 45 min, 2 h, 6 h, 12 h, 24 h, 48 h Result:Induces biphasic MAPK phosphorylation.

Animal Model:Male Wistar rats (250-300 g; 2-3 months) with myocardial infarction (MI)Dosage:0.44 μg/kg 30 min before MI, and 4.4 μg/kg i.v. 24 h prior to MI.Administration:i.v.; once Result:Reduced infarct size and improves rat heart function after myocardial infarct.

UTP | Uridine 5'-triphosphate

Others

Other Targets

Others

Metabolic Disease

Bronchitis; Cystic fibrosis; Lung Cancer; Primary ciliary dyskinesia

63-39-8

484.14

C9H15N2O15P3

>98% (HPLC)

H2O:150 mg/mL (309.83 mM)

O=c1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)[nH]1

(((2R3S4R5R)-5-(24-dioxo-34-dihydropyrimidin-1(2H)-yl)-34-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid

(-20℃)

With Ice Pack

≥ 2 years